The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome (FolicacidPCOS)

University of Khartoum

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Polycystic Ovary Syndrome

Treatments: Drug: Folic Acid

Study type: Interventional

Funder types: Other

Identifiers

NCT03268733

Folic acid in PCOS

Details and patient eligibility

About

An open clinical trial

Full description

The patients with PCOS will be recruited to receive folic acid (45 patients) and equal number will receive no folic acid

Enrollment: 90 estimated patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who will visit this centre suffering from PCOS-related subfertility will be invited to be enrolled to this study if met the Rotterdam criteria for the diagnosis of PCOS

Exclusion criteria

• The patients whom will be excluded from the study are those comorbid with hyperprolactinemia, congenital adrenal hyperplasia, diabetes mellitus, significant cardiovascular problems, thyroid dysfunctions, unresolved medical conditions, or using medications suspected to affect reproductive or metabolic functions within two months of the study entry.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

Treatment group

Experimental group

Description:

45 PCOS patients will receive 5 mg folic acid

Treatment:

Drug: Folic Acid

control group

No Intervention group

Description:

45 PCOS patients will receive no folic acid