The Effects of Frailty on Opioid Consumption

Selcuk University

Status: Completed

Conditions: Opioid Use; Frailty; Knee Arthropathy

Treatments: Device: Patient-controlled analgesia pump (PCA)

Study type: Interventional

Funder types: Other

Identifiers

NCT05445700

2022-1

Details and patient eligibility

About

The FRAIL scale will be applied to patients at the preoperative visit. According to the FRAIL Scale, patients will be divided into 3 groups as Non-frail (Group I), pre-frail (Group II) and frail (Group III). After routine preoperative preparation and monitoring, patients will be given spinal anesthesia. Demographic data and intraoperative data of the patients will be recorded. Patients will be transferred to the post-operational post-operative care unit (PACU) and patient-controlled analgesia (PCA) will be applied to each patient with a standard protocol. In the postoperative period, the need for analgesics will be recorded for 24 hours, and if additional analgesics are needed, they will be recorded. Pain scores of the patients will be evaluated for 24 hours.

Enrollment: 75 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who will undergo unilateral, primary total knee arthroplasty
• Patients who will be operated with spinal anesthesia

Exclusion criteria

• Patients with ASA IV and above physical status
• Uncooperative patients
• Patients who do not speak Turkish
• Patients on routine opioid use

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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75 participants in 3 patient groups

Non-frail

Active Comparator group

Description:

FRAIL scale= 0

Treatment:

Device: Patient-controlled analgesia pump (PCA)

Pre_frail

Active Comparator group

Description:

FRAIL scale= 1-2

Treatment:

Device: Patient-controlled analgesia pump (PCA)

Frail

Active Comparator group

Description:

FRAIL scale \>2

Treatment:

Device: Patient-controlled analgesia pump (PCA)