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The Effects of Ginger Supplementation on Inflammation in Exercising Individuals

Loma Linda University (LLU) logo

Loma Linda University (LLU)

Status

Completed

Conditions

Healthy

Treatments

Dietary Supplement: Ginger

Study type

Interventional

Funder types

Other

Identifiers

NCT03219463
5170187

Details and patient eligibility

About

The purpose of our graduate student research study is to observe the effects of ginger on hsCRP, IL-6, and TNF-α levels in exercising individuals based on their level of activity.

Full description

Participants will fill out a demographic questionnaire and a quality of life survey, (SF-36). Take a 3g supplement of ginger in powder form with meals once/day (preferably in the morning) for 8 weeks. By end of week 4 (halfway through the study), subjects will do another blood test for mid-intervention CRP, IL-6, and TNF-α values. By end of week 8, participants will do a final blood test for CRP values and fill out the SF-36 survey for post-intervention levels.

Enrollment

12 patients

Sex

All

Ages

30 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 30 - 70 years of age

  • Various levels of activity outlined by the General Physical Activities Defined by Level of Intensity by the American College of Sports Medicine (ACSM) and the Centers for Disease Control and Prevention (CDC).

    • Regular Exercisers- at least 30 minutes of moderate to vigorous activity at least 3 times per week.
    • Non-regular Exercisers- at least 30 minutes of moderate to vigorous activity 1-2 times per week.

Exclusion criteria

  • Individuals currently taking...

    • Vit D
    • Aspirin
    • Coumadin
    • Ginger supplements more than 1x/week within the last month
    • Heparin
    • NSAIDs
    • Pain meds
  • Individuals with chronic inflammatory conditions such as Cancer, CVD, Diabetes, Gastroesophageal reflux disease (GERD), Ginger allergies, Metabolic Syndrome, and/or autoimmune diseases such as Rheumatoid Arthritis

Trial design

Primary purpose

Other

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

12 participants in 2 patient groups

Regular Exercise Group
Experimental group
Description:
at least 30 minutes of moderate to vigorous activity at least 3 times per week. Will recieve 3 grams of ginger for 8 weeks.
Treatment:
Dietary Supplement: Ginger
Non Regular Exercise Group
Active Comparator group
Description:
at least 30 minutes of moderate to vigorous activity 1-2 times per week. Will recieve 3 grams of ginger for 8 weeks.
Treatment:
Dietary Supplement: Ginger

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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