The Effects of Glucomannan on Weight Loss

Northeast College of Health Sciences

Status and phase: Completed; Phase 1

Conditions: Obesity

Treatments: Dietary Supplement: Glucomannan; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01709955

10-13

Details and patient eligibility

About

The purpose of this study is to determine if the herb, Glucomannan, is an effective non-pharmacological appetite suppressant for overweight or Class I obese patients. The study design will not include any other lifestyle changes which enhance weight loss in order to completely isolate the effects of Glucomannan as a non-pharmacological appetite suppressant.

Enrollment: 43 patients

Sex: All

Ages: 21 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Subjects will be recruited based upon the category of them wanting to lose 50 pounds.

Subjects must be able to swallow the capsule whole with water.

Exclusion Criteria:

1. Self-reported use of prescription medication other than hormonal birth control (such as medication for diabetes, hypertension hypothyroidism, heart disease, cancer, etc.)
2. Pregnancy
3. Age younger than 21 or older than 60 years of age.
4. Screening for hypertension during the first laboratory visit that reveals a systole greater than 120 and a diastole greater than 90.
5. BMI calculations based upon height and weight measurements at the first laboratory visit that reveal a BMI less than 25 or greater than 35.
6. Self-reported iron-deficiency anemia, osteoporosis, and hypoglycemia.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Triple Blind

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43 participants in 2 patient groups, including a placebo group

Gucomannan

Experimental group

Treatment:

Dietary Supplement: Glucomannan

Placebo pill

Placebo Comparator group

Treatment:

Other: Placebo