The Effects of Gum Chewing on Energy Intake and Expenditure

University of Wisconsin (UW)

Status: Completed

Conditions: Obesity

Treatments: Other: Water; Other: Chewing gum

Study type: Interventional

Funder types: Other

Identifiers

NCT01043471

H-2007-0342

Details and patient eligibility

About

The purpose of this study is to determine if chewing gum increases energy expenditure and decreases food intake.

Enrollment: 31 patients

Sex: Female

Ages: 18 to 38 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 27-37, between the ages of 18 and 38

Exclusion criteria

• History of chronic disease (e.g. liver, kidney, or heart disease, or diabetes)
• Medications that affect energy expenditure, appetite, or body composition (e.g. antidepressants, beta blockers, antipsychotic, or weight loss medications)
• A history of irregular menstrual cycles in women (indication of onset of menopause or other metabolic disturbances such as polycystic ovary syndrome)
• A history of phenylketonuria (PKU)
• Symptoms of depression
• A history of eating disorders
• Concurrent participation in a weight loss program
• Cigarette smoking or other tobacco use
• Jaw problems such as temporomandibular joint disorder (TMJ)
• Allergies to any of the common components in gum (sweeteners, mint flavors, etc)
• Heavy gum chewing prior to study ( > 3 times per week)
• Pregnancy or lactation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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31 participants in 2 patient groups, including a placebo group

Chewing gum

Experimental group

Treatment:

Other: Chewing gum

Water

Placebo Comparator group

Treatment:

Other: Water