The Effects of Hesperidin and Flaxseed in Prediabetes

National Nutrition and Food Technology Institute

Status: Completed

Conditions: PreDiabetes

Treatments: Dietary Supplement: hesperidin and flaxseed; Other: control

Study type: Interventional

Funder types: Other

Identifiers

NCT03737422

6781

Details and patient eligibility

About

To study the effects of Hesperidin and flaxseed supplement in patients with prediabetes, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, inflammatory and anthropometric factors will be assessed and compared between groups.

Enrollment: 48 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age of 18 to 70 years prediabetes: impaired fasting glucose (>100 mg/dL) and/or HbA1C 5.7% to 6.5%, and overweight or obese with body mass index range of 25 to 40 kg/m2

Exclusion criteria

• pregnancy or lactation
• A history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis
• Following program to lose weight in recent 3 mo

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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48 participants in 2 patient groups, including a placebo group

hesperidin and flaxseed

Active Comparator group

Treatment:

Dietary Supplement: hesperidin and flaxseed

control

Placebo Comparator group

Treatment:

Other: control