The Effects of Including Almonds in a Weight Loss Trial

Purdue University

Status: Completed

Conditions: Overweight; Obesity

Treatments: Behavioral: Energy restriction; Behavioral: Almonds (15% kcal/day)

Study type: Interventional

Funder types: Other

Identifiers

NCT02360787

055-030

Details and patient eligibility

About

The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and ameliorate the post-lunch dip in cognitive function.

Full description

The purpose of this study is to determine whether inclusion of almonds in a weight loss regimen will augment the rate of weight loss, promote a greater fat mass/fat-free mass ratio of weight loss, improve blood pressure and ameliorate the post-lunch dip in cognitive function.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Adult participants

• Overweight or obese (BMI 25-40 kg/m2)
• Fasting blood glucose ≤6.9 mmol/L via capillary finger-stick blood samples
• No nut allergies
• Willing to comply to study protocol and to eat test meals

Exclusion criteria

Those not meeting inclusion criteria.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

Energy restriction

Experimental group

Description:

Energy restriction (-500 kcal/day) (N=40), where participants will receive dietary counseling to reduce energy intake to achieve 500 kcal/day deficits to support weight loss. Participants will also be asked to avoid all nuts during the intervention period.

Treatment:

Behavioral: Energy restriction

Energy restriction with almonds

Experimental group

Description:

Energy restriction (-500 kcal/day) with dry-roasted, lightly salted almonds supplying 15% of estimated energy requirement. Participants will receive dietary counseling to reduce energy intake to achieve 500 kcal/day deficits. Energy from almonds will be accounted for during dietary modeling so that a 500 kcal/day deficit is achieved.

Treatment:

Behavioral: Almonds (15% kcal/day)

Behavioral: Energy restriction