The Effects of L-arabinose in a Meal in Healthy Men
Status
Completed
Conditions
Glucose Metabolism
Treatments
Dietary Supplement: L-arabinose - effect on glucose metabolism
Details and patient eligibility
About
The purpose of this study is to investigate the effect of a meal containing different doses of L-arabinose, on the intestinal sucrase activity after intake We measure this by measuring the glucose, insulin and c-peptide after meals. Other measurements are made (glucagon and GLP-1) to explain the correlations.
Enrollment
17 patients
Sex
Male
Ages
18 to 30 years old
Volunteers
Accepts Healthy Volunteers
Inclusion criteria
- Healthy male
- normal weight (BMI 18,5-25 kg/m2)
- 18-30 years of age
Exclusion criteria
- Not healthy,including those with diabetes Mellitus, high bloodpressure, dyslipidemia or a infectious diseases (hepatitis or HIV), gastrointestinal disorders
- Central adipositas (defined as waist circumference > 94 cm for european men)
- Daily intake of vitamins and minerals, 3 months before the trail starts and during the trail.
- elevated alcoholcunsumption(> 21 units af alcohol pr. week)
- take medicine
- Elite athlete with intensive training
- given bloddonation within the last 3 months
- smoking
Trial design
Primary purpose
Prevention
Allocation
Randomized
Interventional model
Crossover Assignment
Masking
Quadruple Blind
17 participants in 6 patient groups
0% arabinose meal sucrose/starch
Experimental group
Description:
A meal containing a bon with butter and marmalade, a cup cake, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
5 % arabinose meal sucrose/starch
Other group
Description:
A meal containing a bon with butter and marmalade, a cup cake, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
10 % arabinose meal sucrose/starch
Other group
Description:
A meal containing a bon with butter and marmalade, a cup cake, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
0 % arabinose meal Starch
Other group
Description:
A meal containing two bons with butter and cheese, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
5 % arabinose meal starch
Other group
Description:
A meal containing two bons with butter and cheese, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
10 % arabinose meal starch
Other group
Description:
A meal containing two bons with butter and cheese, The and water
Treatment:
Dietary Supplement: L-arabinose - effect on glucose metabolism
Trial contacts and locations
0
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Data sourced from clinicaltrials.gov
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