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The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression

University of Michigan logo

University of Michigan

Status

Completed

Conditions

Depression, Postpartum

Treatments

Device: Light therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT02769858
G016030

Details and patient eligibility

About

The proposed study aims to establish the feasibility of light therapy for postpartum depression delivered via Re-Timer, demonstrate its preliminary efficacy, and illuminate relationships between circadian shifts and mood changes using a novel, home-based circadian biomarker assessment paradigm (salivary dim light melatonin onset; DLMO).

Enrollment

10 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Within 6 months postpartum
  • Meet DSM-V diagnostic criteria for MDD
  • Score ≥ 20 on the Structured Interview Guide for the Hamilton Depression Rating Scale-Seasonal Affective Disorder version (SIGH-SAD).

Exclusion criteria

  • current diagnosis of bipolar disorder, posttraumatic stress disorder, schizophrenia or psychosis, dissociative disorders, eating disorder, obsessive-compulsive disorder, somatic symptom and related disorders, substance use disorder, panic disorder, agoraphobia per DSM-V
  • past history of mania/hypomania,
  • chronic medical conditions associated with depression (e.g., thyroid conditions)
  • ocular or retinal pathology
  • history of seizures or epilepsy
  • color blindness
  • Lupus
  • currently taking an antibiotic, medication that contains hydrochlorothiazide, or isotretinoin (Accutane).

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

10 participants in 1 patient group

Light Therapy
Experimental group
Description:
Participants will use commercially-available light therapy glasses (Re-Timer) daily for 60 minutes for five weeks.
Treatment:
Device: Light therapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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