The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients

TriHealth

Status

Completed

Conditions

Interstitial Cystitis

Treatments

Other: MBSR

Study type

Interventional

Funder types

Other

Identifiers

NCT03722992

18-056

Details and patient eligibility

About

This is a prospective cohort study to investigate differences in the bladder environment (i.e. urinary microbiome) amongst women with interstitial cystitis (IC) before and after undergoing mindfulness-based stress reduction (MBSR) treatment, including yoga and meditation practices.

Full description

Interstitial cystitis (IC), or Painful Bladder Syndrome (PBS) is a debilitating condition of the bladder that is estimated to affect 3-8 million women in the United States. The pathophysiology of the disease is poorly understood, and thus treatment modalities and treatment efficacy vary widely. Lately, much attention has shifted toward investigating how the bladder 'environment' differs amongst women with IC compared to those who do not suffer from IC.

Mindfulness-based stress reduction (MBSR), a complementary alternative medicine (CAM)-based therapy, is a standardized program including components of meditation and yoga. Recent studies show that MBSR improves symptoms in the IC patient population.

The purpose of this study is to compare measurable differences in the urinary microbiome among women with IC before and after MBSR treatment.

Enrollment

14 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Adults 18 years of age or older
English-speaking
Established patient of Cincinnati Urogynecology Associates, TriHealth Inc.
Current diagnosis of IC/PBS, as defined by the American Urological Association (AUA)
Negative urinalysis or urine culture within 2 months of enrollment
Currently undergoing first or second-line treatment for IC, as defined by the AUA
Willingness to participate in study

Exclusion criteria

Non-English speaking
Unwillingness to participate in study
Pregnancy or breastfeeding
Physical or mental impairment that would affect the subject's ability to participate in the MBSR treatment, including patients with Dementia, Parkinsonism, or those who have impaired mobility or hearing
Current or expected prolonged catheterization
Expected travel or surgery that would hinder the ability to attend all eight MBSR sessions
Undergoing third-, fourth-, fifth-, or sixth-line treatment for IC as defined by the AUA
Subjects on antibiotics currently or prior use within one week of consenting