The Effects of Multi-modality Physiotherapy in Delaying or Preventing COVID-19 Patient From Admitting to ICU

DR. JASSIM ALGHAITH

Status: Unknown

Conditions: Severe Systemic Illness Respiratory Muscle Fatigue; Covid19

Treatments: Device: Threshold IMT device; Other: Conventional physical therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT04617119

JALGHAITH

Details and patient eligibility

About

This study aims to evaluate the effectiveness of respiratory muscle training with COVID-19 patient, who has underlying health conditions, in order to delay or prevent them from admitting to ICU.

Enrollment: 38 estimated patients

Sex: All

Ages: 21 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Non- intubated patient diagnosed with moderate to severe pneumonia (confirmed by chest x-ray and officially reported) as secondary to COVID-19 with one more symptom such as:

  1. Respiratory rate at ≥ 20 breath.min-1.
  2. Oxygen saturation (SatO2) ≤ 90% at rest on room air.
  3. Arterial partial pressure of oxygen (PaO2) ≤ 80 mmHg at resting.
  4. PaO2/FiO2 ratio or P/F (is the ratio between the arterial partial pressure of oxygen and the percentage of oxygen supplied) < 300mmHg.

Exclusion criteria

1. Patient that has received upper abdominal or thoracic surgery recently (≤ 3 months).
2. Cancer patients.
3. Pregnant patients.
4. Patient mentally unstable.
5. Patient with unstable cardiovascular or neurological functions.
6. Patients refusing to participate in this clinical trial.
7. Patient less the 21 years old (According to Kuwaiti Law).
8. Patients who have a language barrier who cannot understand Arabic or English.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

38 participants in 2 patient groups

Conventional physical therapy treatment and IMT

Experimental group

Description:

The conventional physical therapy treatment for COVID-19 patient will be based on patient medical and physical status. In addition, the patient will receive inspiratory muscle training (IMT) by using a threshold IMT device. Patient will ask to use the device twice daily. In each time, patient will perform 3 sets of 10 breaths with 1-minute rest between sets. Exercise intensity will start with 10 % of pre-measured maximal inspiratory pressure. Once the patient successfully completed 30 breath twice a day, the exercise load will increase 5% more in the subsequent training session. This treatment protocol will perform daily for 2 weeks.

Treatment:

Device: Threshold IMT device

Other: Conventional physical therapy

Conventional physical therapy

Active Comparator group

Description:

The conventional physical therapy treatment for COVID-19 patient will be based on patient medical and physical status.

Treatment:

Other: Conventional physical therapy