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The Effects of Music & Auditory Beat Stimulation on Anxiety

T

Toronto Metropolitan University

Status

Completed

Conditions

Anxiety

Treatments

Behavioral: Auditory Beat Stimulation
Behavioral: Music & Auditory Beat Stimulation
Behavioral: Pink Noise
Behavioral: Music Alone

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT05171218
REB 2020-068

Details and patient eligibility

About

Anxiety is a growing problem and has been steadily increasing, particularly in the adolescent and young adult populations in the past 24 years. Music and auditory beat stimulation (ABS) in the theta frequency range (4-7 Hz) are sound-based anxiety treatments that have been independently investigated in prior studies. Here, the anxiety-reducing potential of calm music combined with theta ABS was examined in a large sample of participants. Participants taking anxiolytics (n = 163) were randomly assigned to a single 24-minute session of sound-based treatment: combined (music & ABS), music-alone, ABS-alone, or pink noise (control). Pre- and post-intervention somatic and cognitive state anxiety measures (STICSA State) were collected along with trait anxiety (STICSA Trait), personality measures (Short Form Eysenck Personality Inventory) and musical preferences (Short Test of Music Preferences).

Full description

In this study, the investigators examined and compared the effectiveness of ABS in the theta range, calm music playlist curated by an affective music recommendation system, and the combination of ABS and the same music to reduce anxiety and stress levels (as measured by the State Trait Inventory for Cognitive and Somatic Anxiety (STICSA)) compared to a control condition (pink noise). Prior work has demonstrated that ABS and music both reduce anxiety when presented on their own. It is hypothesized that music with ABS will lead to significantly lower anxiety levels and increased calmness compared to the other experimental conditions. Approximately 163 participants were recruited from the Prolific online participant pool (https://www.prolific.co). The experiment was conducted on the Qualtrics survey platform, and the experimental treatment was provided with the LUCID Research App. After reading and agreeing with the consent form, participants provided their Prolific ID and then filled out the Short Test of Music Preferences (STOMP), Queen's Music Questionnaire, Anxiety coping method's questionnaire, Positive and Negative Affect Scale (PANAS), Self-Assessment Manikin (SAM), Eysenck Personality Questionnaire, and the State Trait Inventory of Cognitive and Somatic Anxiety (STICSA). Participants were also asked to list any medications currently being taken (including cannabis). Participants were then randomly assigned to one of four treatment groups: (1) music; (2) music and auditory beat stimulation (ABS); (3) auditory beat stimulation (ABS) alone; or (4) pink noise for 24 minutes. Participants then received instructions on how to download the LUCID Research app on their iOS device or access the LUCID Research App through a virtual machine using their computer. Participants listened to their randomly assigned treatment for 24 minutes. Participants then completed their post-intervention questionnaires which included: the STICSA state version, SAM and PANAS. The investigators' hypotheses were that the combined, music alone and ABS alone conditions would experience a greater reduction in somatic and cognitive state anxiety compared to the pink noise control condition. These hypotheses were pre-registered using the Open Science Framework (Registration DOI: https://doi.org/10.17605/OSF.IO/VHCA5) and were based upon previous studies showing that ABS and music listening are capable of reducing anxiety. The investigators had no specific predictions for moderate and high trait anxiety participants, but their pre-registration noted their intention to recruit from both of these populations.

Enrollment

163 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adults (18+)

  • Must be taking anxiety medication

  • Self-identified normal hearing

  • No known cardiac issues

  • No known epilepsy/seizures

    • Have access to an iOS device (iPhone or iPad) to run the Research Application

Exclusion criteria

  • Adults younger than 18

  • Not taking anxiety medication

  • Have known cardiac issues

    • Do not have access to an iOS device (iPhone or iPad) to run the Research Application
  • Have known epilepsy/seizures

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

163 participants in 4 patient groups

Music & Auditory Beat Stimulation
Experimental group
Description:
Participants listened to calm music with theta auditory beat stimulation for 24 minutes
Treatment:
Behavioral: Music & Auditory Beat Stimulation
Music Alone
Active Comparator group
Description:
Participants listened to calm music for 24 minutes
Treatment:
Behavioral: Music Alone
Auditory Beat Stimulation
Active Comparator group
Description:
Participants listened to theta auditory beat stimulation for 24 minutes
Treatment:
Behavioral: Auditory Beat Stimulation
Pink Noise
Sham Comparator group
Description:
Participants listened to pink noise for 24 minutes
Treatment:
Behavioral: Pink Noise

Trial documents
3

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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