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The Effects of Nanomicelles Curcumin on Glycemic Control, Serum Lipid Profile ,Blood Pressure and Anthropometric Measurements in Patients With Metabolic Syndrome

N

National Nutrition and Food Technology Institute

Status

Unknown

Conditions

Metabolic Syndrome

Treatments

Dietary Supplement: placebo
Dietary Supplement: nanomicielle curcumin

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Metabolic syndrome is a condition which is recognized by abdominal obesity, dyslipidemia, hyperglycemia, and hypertension. Curcumin has beneficial effects such as antioxidant and anti-inflammatory effects. nanomcielle curcumin will be used in this study because of the low bioavailability , fast metabolism and low absorption of curcumin powder. Therefore, this study is planned to determine the effects of supplementation of nanomicelle curcumin on glycemic control, serum lipid profile ,blood pressure and anthropometric measurements in patients with metabolic syndrome.

Enrollment

50 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 25<body mass index >40
  • waist circumference >102 cm in men or >88 cm in women
  • Fasting blood glucose >100 mg/dL
  • Triglycerides (TG) > 150 mg/dL
  • High density lipoprotein cholesterol (HDL-C) <50 in women or <40 in men
  • Systolic blood pressure (SBP) >130 mmHg and diastolic blood pressure (DBP) >85mmHg

Exclusion criteria

  • insulin administration for diabetes control
  • hypo- or hyperthyroidism,
  • renal failure or other chronic diseases
  • pregnancy and breastfeeding
  • taking weight loss supplements and obeying unusual weight loss plans

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

50 participants in 2 patient groups, including a placebo group

nanomicielle curcumin
Active Comparator group
Treatment:
Dietary Supplement: nanomicielle curcumin
plecebo
Placebo Comparator group
Treatment:
Dietary Supplement: placebo

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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