The Effects of Over-the-Counter Products on the Skin

Johns Hopkins University

Status: Withdrawn

Conditions: Skin Health

Treatments: Other: Supportive care with OCT product

Study type: Interventional

Funder types: Other

Identifiers

NCT03641430

IRB00180361

Details and patient eligibility

About

The primary purpose of this study is to investigate the safety and tolerability of commonly used over-the-counter products and the effects of the products on skin health.

Full description

Participant will apply commonly used skin product on skin for a period of time with or without light challenge. The investigators will perform clinical assessments of the skin associated with product application as well as assess these changes with and without light challenge. Skin biopsies will be obtained following standard medical practice and will be used to analyze skin markers related to photoaging, pigmentation, oxidative stress, and other dermatologic conditions.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants must be over the age of 18 years old with healthy skin;
• Participant must be willing and comply with the requirements of the protocol;
• Participant must have the ability to understand and communicate with the investigator;
• Participant must provide informed consent.

Exclusion criteria

• Subjects who are unable to provide informed consent;
• Subject with significant medical history or current skin diseases that the investigator feels is not safe for study participation;
• Subjects who self-report that they are pregnant or nursing;
• Subjects who do not speak English or have difficulty hearing or are otherwise impaired for providing informed consent and communicating with the investigator;
• Subjects with known bleeding disorders or diathesis;
• Subjects with a history of keloids or excessive scarring;
• Subjects with known allergy to lidocaine, epinephrine, or any of the tested products;
• Subjects who foresee intensive UV exposure during the study (e.g. sunbathing, tanning beds).

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

Supportive care with Over-the-Counter (OCT) product

Experimental group

Description:

Participants will apply over-the-counter product for a certain period with or without light challenge

Treatment:

Other: Supportive care with OCT product