The Effects of PeptiStrong and Whey on Muscle Function In Older Adults

Nuritas

Status: Enrolling

Conditions: Muscle Function; Peptides; Hand Grip Strength; Longevity; Muscle Health; Protein Supplementation; Healthy Ageing

Treatments: Dietary Supplement: Whey protein; Dietary Supplement: PeptiStrong + whey protein

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT07528469

PEPVFH+60/26

Details and patient eligibility

About

Examining the effects of PeptiStrong and protein on muscle function in older adults

Full description

The aim of this study is to compare two protein drinks containing whey protein (derived from milk) in healthy adults aged 60 to 85 years. One group will consume a standard whey protein drink (20g), while the other group will consume a drink with half the total protein dose (10g) made of whey protein and PeptiStrong, a fava bean hydrolysate containing bioactive peptides.

The study will assess whether the lower protein drink containing PeptiStrong will lead to equal or greater improvements than the standard drink in physical function, such as the ability to stand up from a chair, walk at a normal pace, maintain balance, and grip strength. The study will also examine markers related to inflammation, fatigue, and quality of life.

The intended value of this research is to improve understanding of how targeted nutritional strategies may help maintain or improve muscle function in older adults. The findings may help inform future nutritional recommendations and the development of practical dietary interventions aimed at supporting healthy ageing and independence.

Enrollment: 80 estimated patients

Sex: All

Ages: 60 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women aged 60 to 85 years at the time of enrolment
• Community-dwelling (living independently or with minimal assistance)
• Able to walk independently (with or without a walking aid) and complete simple physical function tests (such as standing up from a chair and walking short distances)
• Willing and able to attend two study visits at the research facility (baseline and end of study)
• Willing and able to consume a protein drink containing whey protein (derived from milk) once daily for 30 days
• Able to understand the study information and provide written informed consent

Exclusion criteria

• Any known food allergy or intolerance to fava bean protein or milk protein
• Diagnosed kidney disease or any medical condition where increased protein intake is contraindicated
• Yes to any of the answers on the "Older Adult Functional Assessment Screening Questionnaire"
• Individuals with implanted electronic devices
• Current or recent (within the past 3 months) participation in another clinical research study involving a nutritional or exercise intervention
• Conditions that significantly impair mobility or balance such that safe completion of the physical function tests is not possible

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

80 participants in 2 patient groups

PeptiStrong + whey protein

Experimental group

Description:

2.4g PeptiStrong (provides 1.6g protein) + 8.4g of whey protein = 10g total protein

Treatment:

Dietary Supplement: PeptiStrong + whey protein

Whey protein

Active Comparator group

Description:

20g whey protein

Treatment:

Dietary Supplement: Whey protein