The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients

Taibah University

Status and phase: Completed; Phase 4

Conditions: Chronic Periodontitis, Generalized

Treatments: Combination Product: amoxicillin 500mg and metronidazole 400mg

Study type: Interventional

Funder types: Other

Identifiers

NCT03783845

periodontal therapy and HbA1c

Details and patient eligibility

About

Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?

Full description

The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes.

Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group

Enrollment: 44 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis

Exclusion criteria

Pregnancy

• Alcoholism and smoking
• Presence of any systemic disorders other than hypertension and diabetes
• Diabetic major complications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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44 participants in 2 patient groups

test group

Experimental group

Description:

Metronidazole 400mg,three times daily for two weeks Amoxicillin 500mg,three times daily for two weeks.

Treatment:

Combination Product: amoxicillin 500mg and metronidazole 400mg

control group

No Intervention group

Description:

no intervention during study period