The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms

Tabriz University

Status and phase: Completed; Phase 2

Conditions: Gingivitis

Treatments: Drug: Placebo; Drug: Chlorhexidine; Drug: pistacia Mutica extract

Study type: Interventional

Funder types: Other

Identifiers

NCT00972803

8660

Details and patient eligibility

About

Dental plaque is a well known etiologic factor for gingivitis. Recently, herbal extracts are a matter of scientific interest to inhibit plaque accumulation on teeth. The purpose of this study was to evaluate the effects of pistacia Mutica (PM) mouth wash on de novo dental plaque plaque formation, gingival inflammation indices and oral microorganisms.

Enrollment: 25 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• had merely gingivitis (pocket depth≤3 mm, no attachment loss)
• without any fixed or removable oral appliances

Exclusion criteria

• Individuals who had a history of any relevant systemic diseases
• Individuals who had a history of any drug usage

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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25 participants in 3 patient groups, including a placebo group

pistacia Mutica

Experimental group

Description:

The subjects were asked to use a mouthwash containing pistacia Mutica extract twice a day for 4 days.

Treatment:

Drug: pistacia Mutica extract

placebo

Placebo Comparator group

Description:

The subjects were asked to use a mouthwash containing Placebo twice a day for 4 days.

Treatment:

Drug: Placebo

Chlorhexidine

Active Comparator group

Description:

The subjects were asked to use a mouthwash containing Chlorhexidine twice a day for 4 days.

Treatment:

Drug: Chlorhexidine