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The Effects of Position on the Oxygenation Instability of Premature Infants as Documented by SpO2 Histograms

R

Rambam Health Care Campus

Status

Completed

Conditions

Bronchopulmonary Dysplasia
Premature Infant

Treatments

Procedure: Position change

Study type

Interventional

Funder types

Other

Identifiers

NCT03546543
0167-17-RMB

Details and patient eligibility

About

SpO2 instability is in the nature of premature infants. Hypoxic episodes occur spontaneously in many of these infants, especially after the first week of life. Different interventions have been shown to influence the incidence of hypoxemic episodes in premature infants. A few studies point towards potential clinical benefits of better oxygenation and less hypoxic events by positioning very low birth weight infants prone, though a recent meta-analysis didn't find a clear benefit of prone position.

The aim of this study is to evaluate the changes in oxygenation among preterm infants receiving respiratory support when positioned prone versus supine, as documented by SpO2 histograms.

Enrollment

23 patients

Sex

All

Ages

14+ days old

Volunteers

No Healthy Volunteers

Inclusion criteria

Premature infants with a weight < 1500 g who are receiving respiratory support

Exclusion criteria

Congenital anomalies, acute lung pathology for example x-ray confirmed pneumonia, air leak, active culture proven sepsis or on inotropic support for low blood pressure.

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

23 participants in 2 patient groups

Supine
Experimental group
Treatment:
Procedure: Position change
Prone
Experimental group
Treatment:
Procedure: Position change

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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