The Effects of Potassium on Physiological and Cardiovascular Variables in Healthy Persons

Erling Bjerregaard Pedersen

Status and phase: Completed; Phase 1

Conditions: Hypertension

Treatments: Drug: Calcium; Drug: Potassium

Study type: Interventional

Funder types: Other

Identifiers

NCT00801034

MED.RES.HOS.2008.01.SKM

Details and patient eligibility

About

In humans living of fruit and vegetables, hypertension is rarely seen. We wish to study if the development of hypertension has a connection to our intake of potassium. We know that fruit and vegetables contain a lot of potassium and we will simulate this intake by giving healthy subjects potassium as tablets.

Enrollment: 25 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy
• age 18-40 years old
• BMI 18, 5-30
• non-smoker

Exclusion criteria

• daily use of medicine
• alcohol or drugs
• desire to become pregnant
• not using safe anti-contraceptive
• abnormal results in the initial testing

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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25 participants in 2 patient groups, including a placebo group

1

Placebo Comparator group

Description:

Calcium tablets

Treatment:

Drug: Calcium

2

Active Comparator group

Description:

Potassium tablets

Treatment:

Drug: Potassium