The Effects of Protein Supplementation in Females and Males Following Acute Eccentric Exercise

Liverpool John Moores University

Status: Completed

Conditions: Muscle Damage

Treatments: Other: Drop Jumps

Study type: Interventional

Funder types: Other

Identifiers

NCT04679519

16/SPS/007

Details and patient eligibility

About

Examine the impact of the protein supplements leucine, HMB and BCAA on muscle recovery and inflammatory response following acute exercise.

Full description

Participants, both females and males, will perform an acute bout of exercise. A bout of exercise that will involve multiple drop jumps. Prior to and post exercise, functional outputs will be measured and blood will be collected to quantify the inflammatory response. The protocol will involve attending the laboratory on 6 occasions over a two week period to complete the above measures.

Enrollment: 90 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Health recreationally active males and females.

Exclusion criteria

• Asthma sufferers
• People with kidney disease
• People partaking in lower limb strength training
• People suffering DOMS in the past 6 months
• People already taking dietary supplements, other NSAIDs, or for example aspirin, alcohol, warfarin, phenytoin, methotrexate, lithium, diuretics, cyclosporine.
• People with bone or soft tissue injury within last 12 months
• People with gastric problems
• People with hypertension
• People who have had history of heart failure
• People with liver disease
• People with connective tissue disorders
• People with Crohn's disease
• People with ulcerative colitis
• People with peripheral arterial disease
• People with cerebrovascular disease
• Elderly population
• People with allergies to NSAIDs, Omega- 3 fatty acids and BCAAs.
• People with depression
• People with bipolar disorder
• People with diabetes
• Females who are pregnant
• People who have HIV / AIDS

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 4 patient groups

Control

Active Comparator group

Description:

Control group that was not given a supplement.

Treatment:

Other: Drop Jumps

BCAA

Experimental group

Description:

Supplement group that was given Branched Chain Amino Acids (BCAA).

Treatment:

Other: Drop Jumps

Leucine

Experimental group

Description:

Supplement group that was given Leucine.

Treatment:

Other: Drop Jumps

HMB

Experimental group

Description:

Supplement group that was given β-Hydroxy β-methylbutyric acid (HMB)

Treatment:

Other: Drop Jumps