ClinicalTrials.Veeva

Menu

The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19

T

Tehran University of Medical Sciences

Status

Completed

Conditions

Covid-19
Pneumonia
SARS Pneumonia

Treatments

Other: Pulmonary Physiotherapy Techniques

Study type

Interventional

Funder types

Other

Identifiers

NCT04357340
99-1-103-47429

Details and patient eligibility

About

The aim of this study is to evaluate the efficacy of pulmonary physiotherapy on respiratory functions in hospitalized patients with Novel Coronavirus 2019 pneumonia. Patients will be randomized into 1) intervention group: receiving pulmonary physiotherapy technique to improve pulmonary function and walking training or 2) control group: Usual medical care. Patients in both groups will receive therapeutic incentive spirometer. Various outcome measurements of pulmonary functions will be evaluated before and after of interventions. Mortality rate, hospitalization duration and re-admission will be followed until one month after end of intervention. Also, patient's quality of life will be measured after one month.

Full description

In late December 2019, the new coronavirus (COVID-19) emerged in Wuhan, China and it has been confirmed as the cause of pneumonia in a large number of Chinese patients. The virus, also known as SARS-CoV-2, has since then spread to more than 200 countries worldwide.

The most common symptoms of COVID-19 are fever, dry cough, shortness of breath and tiredness. In severe cases, the infection could cause pneumonia, acute respiratory distress syndrome (ARDS) and sometimes leads to death. Pulmonary physiotherapy is a comprehensive, effective and safe treatment method which is aimed at improving patient's respiratory symptoms, train effective coughing, clear the airway secretion, eliminate exacerbation and so on. It seems that pulmonary physiotherapy interventions can effectively decrease hospitalization, reduce the risk of complications and improve the patient's medical condition.

The aim of this study is to evaluate the effectiveness of the hold breathing technique, chest expansion exercise, postural drainage procedure and Cough techniques carried out during pulmonary physiotherapy sessions.

The researchers will invite 40 hospitalized patients in Imam Khomeini Hospital Complex, Tehran, Iran. All patients will be enrolled after taking informed consent. All of the procedure will be performed with the coordination of the patient's physicians. Patients will be randomized to the intervention or control group. Primary outcome measurements will be evaluated immediately before and after the interventions (with three days period). Also, patient's condition (including process of disease progression, mortality, hospital stay duration and re-admission) will be followed until one month using medical records review and interviewing with the patient or his/her family. Patient's health related quality of life will be measured using short form-36 quality of life assessment tool one month after the end of interventions. Intention-to-treat analysis will be performed in the patients that dropped out of the study.

Enrollment

40 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Patients with COVID-19 pneumonia confirmed by RT-PCR test and diagnostic radiology.
  2. Non-intubated patients
  3. Patients with full consciousness
  4. Be able to walking and performing exercises.
  5. O2 Saturation < 88% when free air breathing.
  6. be able to write and read in Farsi

Exclusion criteria

  1. Any type of musculoskeletal disorder disabling patient to participate to study.
  2. Intubation during the period of intervention
  3. Patients' dissatisfaction to continue the study for any reason.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

40 participants in 2 patient groups

Pulmonary Physiotherapy Techniques group
Experimental group
Description:
Pulmonary physiotherapy techniques, 6 sessions during 3 days and incentive spirometer.
Treatment:
Other: Pulmonary Physiotherapy Techniques
Control group
No Intervention group
Description:
Incentive spirometer only

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems