The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery

Nordsjaellands Hospital

Status: Completed

Conditions: Myocardial Injury After Non-cardiac Surgery; Troponin I; Emergency Surgery; Myocardial Injury; Abdomen, Acute

Treatments: Diagnostic Test: Troponin I

Study type: Observational

Funder types: Other

Identifiers

NCT05992961

P-2020-507-2

Details and patient eligibility

About

Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury after non-cardiac surgery (MINS) and mortality. The majority of patients with MINS will not experience any symptoms, and thus MINS remains undetected without routine troponin measurements.

The investigators hypothesized that implementing surveillance with troponin I as a standard care might be useful as risk stratification, and that increased surveillance, examinations, and subsequent individually based medical interventions, might improve the outcomes for patients with MINS.

Enrollment: 558 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eligible patients were 18 years or older
• Undergoing surgery for gastrointestinal perforation, obstruction, mesenterial ischemia or necrosis, or anastomotic leakage.

Exclusion criteria

• Not undergoing surgery for one of the conditions above

Trial design

558 participants in 2 patient groups

Patients not undergoing troponin I surveillance

Description:

Patients undergoing acute high-risk abdominal surgery during the period February 1, 2018, to February 28, 2019. No troponin I measurements were made.

Patients undergoing troponin I surveillance

Description:

Patients undergoing acute high-risk abdominal surgery during the period March 1, 2019, to February 28, 2021 as well as postoperative troponin I surveillance .

Treatment:

Diagnostic Test: Troponin I