The Effects of Vitamin D2 Supplement During Pregnancy

Rajavithi Hospital

Status: Completed

Conditions: Pregnancy Early

Treatments: Drug: Placebo; Drug: Calciferol

Study type: Interventional

Funder types: Other

Identifiers

NCT03743922

THAIVITD2

Details and patient eligibility

About

The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial

Full description

Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week

Enrollment: 60 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women who have pregnant and ANC at Rajavithi hospital
• Women who have age at least 18 year
• Women who have Thai nationality
• Women who have pregnant of gestational age under 20week

Exclusion criteria

• Women who don't plan of delivered at Rajavithi hospital
• Women who have complication of pregnancy
• Woman who delivered before gestational age 37week
• Women who have abnormal kidney function
• Woman who have been used anticonvulsant drug or others form of vitamin d
• Women who have vitamin d allergy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups, including a placebo group

Oral calciferol group

Experimental group

Description:

Subjects will receive oral calciferol 20,000 iu per week during pregnancy until delivered

Treatment:

Drug: Calciferol

oral placebo group

Placebo Comparator group

Description:

Subjects will receive oral placebo 1 tab per week during pregnancy until delivered

Treatment:

Drug: Placebo