The Effects of Weight Loss on Psoriatic Arthritis

Hacettepe University

Status: Completed

Conditions: Obesity; Psoriatic Arthritis

Treatments: Behavioral: diet and biopsychosocial exercise intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT05393141

HU-SO-2022

Details and patient eligibility

About

Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into "diet", "diet+bety", and "control" groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.

Full description

Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms.

• Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups.
• Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian.
• BETY exercise training will be given by a registered physiotherapist.
• The subjects will be followed for 12 weeks.
• Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.

Enrollment: 48 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• overweight/obese
• diagnosed with PSA

Exclusion Criteria

• pregnancy or lactation

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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48 participants in 3 patient groups

diet group

Experimental group

Description:

weight loss diet intervention for 12 weeks

Treatment:

Behavioral: diet and biopsychosocial exercise intervention

diet+bety group

Experimental group

Description:

weight loss diet intervention for 12 weeks and exercise-based biopsychosocial approach (Cognitive Exercise Therapy Approach-BETY) intervention for 12 weeks

Treatment:

Behavioral: diet and biopsychosocial exercise intervention

control group

No Intervention group

Description:

no intervention, control