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The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia

McMaster University logo

McMaster University

Status

Completed

Conditions

Old Age; Dementia
Neuro-Degenerative Disease
Parkinson Disease
Cough
Swallowing Disorder

Treatments

Behavioral: Whole-body exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT04362228
REB project #10638

Details and patient eligibility

About

Swallowing impairment (dysphagia) is extremely common in older adults living with dementia due to age-related changes in swallowing and other disease-specific impairments. Dysphagia is commonly managed by modifying diet textures rather than engaging in rehabilitative swallowing therapy. This means that countless people with dementia are left to eat pureed foods and drink thickened liquids, which are unpalatable and lead to malnutrition. As the disease progresses, many are transferred to nursing homes. In Canada, speech-language pathologists, who manage dysphagia, are consultants within nursing homes; therefore, swallowing therapy is non-existent. However, exercise therapy is more commonly available. Rodent models have demonstrated that physical exercise strengthens tongue and vocal-fold musculature, which are critical components of swallowing. Therefore, it is possible that whole-body physical exercise, which increases rate of respiration, will help to strengthen swallowing-related musculature in older adults with dementia. In this study, older adults (65+) with early-stage dementia will complete a 12-week physical exercise program to determine improvement of swallowing function.

Enrollment

9 patients

Sex

All

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • > 59 years of age
  • able to walk independently with or without an assistive device for a distance of at least 10 meters
  • able to be active for 60 minutes with rest breaks
  • abe to independently follow directions
  • not involved in active rehabilitation
  • a diagnosis of a progressive neurologic disease
  • a maximum value for tongue strength <40 kPa

Exclusion criteria

  • neurological conditions other than a progressive neurologic disease
  • significant cardiovascular conditions
  • severe aphasia
  • pain, other medical conditions or behavioural issues that would limit safe participation in the exercise program
  • individuals with known structural causes of dysphagia
  • individuals with known allergies to latex
  • individuals receiving swallowing rehab

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

9 participants in 1 patient group

Whole-body exercise
Experimental group
Treatment:
Behavioral: Whole-body exercise

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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