The Effects of Whole Versus Processed Orange Consumption on Satiety

University of Reading

Status: Completed

Conditions: Satiety Response

Treatments: Dietary Supplement: Processed orange juice

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02288624

UOR-0002

Details and patient eligibility

About

This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.

Full description

This is a human dietary intervention study that is randomized and crossover in design with 4 treatment arms consisting of control, orange juice,whole orange, and processed whole orange to investigate the satiety effects of the treatments in healthy volunteers. Self reported hunger and fullness scores by Visual Analogue Scale (VAS) form were collected at different time points prior to and post consumption of each treatment.

Enrollment: 24 patients

Sex: All

Ages: 21 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Gender: male or female(postmenopausal women only)
• Age at start of the study: males ≥ 21and ≤ 65 years and females ≥ 50 and ≤ 65 years
• Body Mass Index (BMI) ≥ 18.5 and ≤ 27 kg/m2
• Apparently healthy: measured by questionnaire, no reported current or previous metabolic diseases or chronic gastrointestinal disorders
• Reported dietary habits: no medically prescribed diet, no slimming diet, used to eating 3 meals a day
• Reported intense sporting activities ≤ 10h/w
• Reported alcohol consumption ≤21 units/w
• Informed consent signed
• Recruitment form filled out

Exclusion criteria

• Smoking
• Dislike, allergy or intolerance to test products
• Possible eating disorder (measured by SCOFF questionnaire score >1)
• Eating habits questionnaire score >14
• Reported medical treatment that may affect eating habits/satiety
• Pre menopausal women

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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24 participants in 4 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

Water control (240 ml)

Treatment:

Dietary Supplement: Processed orange juice

Orange Juice

Experimental group

Description:

Orange juice, 240 ml. Commercial orange juice

Treatment:

Dietary Supplement: Processed orange juice

Whole orange

Experimental group

Description:

Whole orange, 240 ml. Whole orange, blended to include all edible orange material.

Treatment:

Dietary Supplement: Processed orange juice

processed orange juice

Experimental group

Description:

Processed orange juice, 240 ml. Experimental orange juice processing

Treatment:

Dietary Supplement: Processed orange juice