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The Effects of Wild Blueberries on Depressive Symptoms in Young Adults (BluMood)

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University of Reading

Status

Completed

Conditions

Anhedonia
Depression
Anxiety

Treatments

Dietary Supplement: Placebo powder
Dietary Supplement: Wild blueberry powder

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

This study aims to investigate the effects of a 6-week dietary intervention of 22 g freeze-dried whole wild blueberry powder. The outcomes include measures of depression, anxiety, anhedonia, cognitive function, and biomarkers of inflammation and oxidative stress.

Full description

A randomized, double-blind, placebo-controlled, parallel-design study assessing the effects of a 6-week intervention of wild blueberry powder in young adults with depressive symptoms. A total of 60 participants will be randomly assigned to either 22 g blueberry powder or a matched placebo powder consumed daily with water. The severity of depression, anxiety, anhedonia, perceived stress, and quality of life will be measured at baseline and 6 weeks later. In addition, we will assess changes in cognitive function and transient mood 2 hours after consuming a single dose of blueberries.

Enrollment

62 patients

Sex

All

Ages

18 to 24 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • 18 to 24 years of age
  • Patient Health Questionnaire-9 score ≥ 10 and a score ≥ 2 on the sum of items 1 and 2
  • Willingness to provide blood samples

Exclusion criteria

  • Any medically significant condition (e.g. diabetes, endocrine or gastrointestinal disorders)
  • Taking medication (excluding hormonal contraception)
  • History of mental illness (excluding anxiety and unipolar depressive disorders)
  • Allergy to blueberries or any other Vaccinium species
  • Receiving psychotherapy or counselling

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

62 participants in 2 patient groups

Blueberry powder
Experimental group
Treatment:
Dietary Supplement: Wild blueberry powder
Placebo powder
Experimental group
Treatment:
Dietary Supplement: Placebo powder

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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