The Effects of Zn-containing Granulate on Patient Morbidity and Wound Healing After Free Gingival Graft Surgery

Çukurova University

Status: Completed

Conditions: Surgery

Treatments: Procedure: Zn granulate stent after FGG surgery; Procedure: Hemostatic agent suturing

Study type: Interventional

Funder types: Other

Identifiers

NCT05684913

CukurovaU-4

Details and patient eligibility

About

There is no study in the literature showing the effects of Zn on wound healing after free gingival graft (FGG) operation. The aim of this randomized clinical study was to compare the early healing results of the palatal wound after FGG harvesting by sterile hemostatic agent suturing or the use of surgical stent from thermoplastic Zn-containing granules which was prepared chairside.

Full description

There are many studies reporting paresthesia, herpetic lesion, mucocele, excessive bleeding and severe postoperative pain after procedure.The highest pain level perceived in the palatal region after the FGG operation is experienced on the first day after the operation and decreases to the preoperative levels approximately 2 weeks after the operation. Although hemostatics, bioactive substances, antibacterial and antiseptic agents, herbal effective products, platelet concentrations, low-dose laser applications, palatal stents are used in the palatal region to accelerate the healing stages and prevent such complications, an ideal support has not been found.

Enrollment: 60 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Periodontal and systemically healthy

  • ≥19 years old
  • Amount of attached gingival width in the maxillary or mandibular anterior region <2 mm
  • Full mouth plaque index score, bleeding index score on full-mouth probing <15%

Exclusion criteria;

• Previously undergone surgery for a graft harvested from the palate
• Presence of systemic disease
• Taking medication known to interfere with periodontal health
• Smoking

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Zinc granulate group

Experimental group

Description:

The patients in this group will receive a chair-side prepared surgical stent from Zn granulates on the palatal wound after FGG surgery.

Treatment:

Procedure: Zn granulate stent after FGG surgery

Hemostatic agent group

Active Comparator group

Description:

The patients in this group will receive hemostatic agent sutured on the palatal wound after FGG surgery.

Treatment:

Procedure: Hemostatic agent suturing