The Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combinded With Zinc Supplement

Siriraj Hospital

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Female Pattern Alopecia

Treatments: Drug: 15 mg Chelate zinc supplement; Drug: Placebo drug supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT01662089

SirirajH-004

Details and patient eligibility

About

Zinc supplement is a popular trace element gave to Female pattern hair loss (FPHL) patient. But the type of patient, efficacy, and side effect in detail of zinc supplement are not well characterized. The purpose of this study is to determine efficacy and side effect of chelated zinc in FPHL who using 5%minoxidil solution.

Full description

5%minoxidil solution is standard treatment for Female pattern hair loss (FPHL) patient. We gave 15mg chelate Zinc / Placebo drug to patient as an additional trace element. Then measure growth of hair by Global photograph, Microscope hair count, micrometer and record case and side effect during 10 months of treatment.

Enrollment: 20 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female Pattern Hair Loss ( Ludwig classification grade 1 and 2 )

Exclusion criteria

• Underlying disease ; Anemia, Diabetes, chronic alcoholism, previous gastrointestinal surgery, short bowel syndrome, Crohn's disease, digestive disorder, hypo/hyperthyroidism, sickle cell disease, autoimmune disease, iron deficiency
• Psychologic disorder trichotillomania
• Diet control
• Pregnancy or lactation
• On supplement diet within 3 month prior to trial

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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20 participants in 2 patient groups, including a placebo group

Chelate zinc suppliment

Experimental group

Description:

15mg Chelate zinc suppliment : additional to standard 5% minoxidil

Treatment:

Drug: 15 mg Chelate zinc supplement

Placebo drug

Placebo Comparator group

Description:

Placebo drug to compare with 15mg chelated Zn : additional to standard 5% minoxidil

Treatment:

Drug: Placebo drug supplement