The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty

Rigshospitalet

Status and phase: Completed; Phase 4

Conditions: Total Knee Arthroplasty

Treatments: Procedure: Adductor-Canal-Blockade; Procedure: Adductor-Canal-blockade with saline

Study type: Interventional

Funder types: Other

Identifiers

NCT01104883

SM1-PJ-2009

2009-017794-37 (EudraCT Number)

Details and patient eligibility

About

The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing morphine consumption and pain, and at the same time improving mobilisation after total knee arthroplasty.

Enrollment: 70 estimated patients

Sex: All

Ages: 50 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Total Knee Arthroplasty in spinal anaesthesia
• ASA 1-3
• BMI 18-40
• Written informed consent

Exclusion criteria

• Can not cooperate to the exam
• Do not speak or understand Danish
• Drug allergy
• Alcohol or drug abuse
• Daily consumption of strong opioids
• Unable to complete the Timed Up and Go test preoperatively

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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70 participants in 2 patient groups, including a placebo group

Adductor-Canal-Blockade

Experimental group

Description:

Adductor-Canal-Blockade with ropivacaine

Treatment:

Procedure: Adductor-Canal-Blockade

Adductor-Canal-blockade with saline

Placebo Comparator group

Description:

Adductor-Canal-blockade with isotonic saline

Treatment:

Procedure: Adductor-Canal-blockade with saline