The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty

Rigshospitalet

Status and phase: Completed; Phase 4

Conditions: Knee Arthroplasty; Postoperative Pain

Treatments: Procedure: Adductor-Canal-Blockade with Ropivacaine; Procedure: Adductor-Canal-blockade with saline

Study type: Interventional

Funder types: Other

Identifiers

NCT01261897

2010-021918-30 (EudraCT Number)

SM2-PJ-10

Details and patient eligibility

About

The objective of this study is to assess the efficacy of Adductor-Canal-Blockade on pain and morphine consumption after total knee arthroplasty. Our hypothesis is that the Adductor -Canal-Blockade is superior to placebo in reducing pain and morphine consumption after total knee arthroplasty.

Enrollment: 40 estimated patients

Sex: All

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Total Knee Arthroplasty in general anaesthesia
• ASA 1-3
• BMI 18-40
• Written informed consent

Exclusion criteria

• Can not cooperate to the exam
• Do not speak or understand Danish
• Drug allergy
• Alcohol or drug abuse
• Daily consumption of strong opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

40 participants in 2 patient groups, including a placebo group

Adductor-Canal-Blockade with Ropivacaine

Active Comparator group

Treatment:

Procedure: Adductor-Canal-Blockade with Ropivacaine

Adductor-Canal-blockade with saline

Placebo Comparator group

Treatment:

Procedure: Adductor-Canal-blockade with saline