The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome

Asan Medical Center

Status: Completed

Conditions: Interstitial Cystitis

Study type: Observational

Funder types: Other

Identifiers

NCT01985880

2013-0616

Details and patient eligibility

About

The purpose of this study is to evaluate efficacy of biomarker in patient with interstitial cystitis/painful bladder syndrome

Full description

This is a observational study

Enrollment: 67 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. must have experienced bladder pain, urinary urgency and urinary frequency, for at least 6 months prior to entry into the study 2) Pain VAS ≥4 3) O'Leary-Sant Interstitial Cystitis questionnaire (IC-Q) symptom and problem ≥ 12( and pain ≥2, and nocturia ≥ 2) 4) PUF score ≥ 13 5) cystoscopic record within 2 years

Exclusion criteria

1. Patients who are pregnancy or, childbearing age without no contraception

2. Patients with voided volume <40 or, > 400ml

3. Patients with microscopic hematuria, (≥1+ in dipstick), If not excluded that no evidence of neoplastic tumor examination

4. Patients with urine culture showing evidence of urinary tract infection 1month prior to the study

5. Accompanied medical problem below

   • Tuberculosis in urinary system
   • Bladder cancer, urethral cancer, prostate cancer
   • Recurrent cystitis
   • anatomical disorder

6. Patients had prior surgery (eq, bladder augmentation, cystectomy

7. Patients with neurologic disorder

8. Patients with indwelling catheter or intermittent self-catheterization

9. Patients with psychologic problem

Trial design

67 participants in 3 patient groups

Hunner's ulcer interstitial cystitis

Description:

Hunner's ulcer interstitial cystitis

non-ulcer interstitial cystitis

Description:

non-ulcer interstitial cystitis

Control

Description:

Control