The Efficacy of Fenugreek Supplementation on Men's Health

Jacksonville University

Status: Completed

Conditions: Aging; Testosterone Deficiency

Treatments: Dietary Supplement: AlphaFen fenugreek 400 mg; Dietary Supplement: AlphaFen fenugreek 500 mg; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03528538

JUFenugreek2018

Details and patient eligibility

About

1. The problem: There is limited research on the use of herbal supplements in general, and fenugreek specifically, to improve male health, particularly to increase testosterone levels. As well, no located studies have examined the effects of fenugreek supplementation on healthy men's health-related quality of life, anxiety levels, and body composition.
2. Relevant research examined the effects of fenugreek supplementation with healthy men aged between 43 and 70 years of age. The researchers found that both total serum testosterone and free testosterone increased compared to placebo after 12 weeks of active treatment. The researchers concluded that fenugreek supplementation was a safe and effective treatment for reducing symptoms of possible androgen deficiency, improves sexual function and increases serum testosterone in healthy middle-aged to older men. Another study found that fenugreek supplementation improved aging male symptoms and testosterone levels remained in a normal range in healthy men aged 25 to 45 years.
3. The importance of this study: The importance of this study is to help determine if fenugreek supplementation affects testosterone levels, body composition, health-related quality of life, anxiety, and aging symptoms in healthy men aged 21 - 45 years.

Enrollment: 58 patients

Sex: Male

Ages: 21 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men between the ages of 21- 45 that were recreationally active.

Exclusion criteria

• Above 30% body composition, not in the age range, history of asthma, diabetes, hypoglycemia, or took any hormonal supplements such as testosterone or anabolic steroids.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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58 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Treatment:

Other: Placebo

AlphaFen fenugreek 400 mg

Active Comparator group

Description:

This group received 400 mg of fenugreek to be ingested daily for 60 days.

Treatment:

Dietary Supplement: AlphaFen fenugreek 400 mg

AlphaFen fenugreek 500 mg

Active Comparator group

Description:

This group received 500 mg of fenugreek to be ingested daily.

Treatment:

Dietary Supplement: AlphaFen fenugreek 500 mg