The Efficacy of Pantoprazole Treatment in Patients With Functional Dyspepsia

Bezmialem Vakif University

Status and phase: Unknown; Phase 4

Conditions: Nonulcer Dyspepsia

Treatments: Drug: Folic Acid; Drug: Pantoprazol

Study type: Interventional

Funder types: Other

Identifiers

NCT01608750

B.30.2.BAV.0.05.05/331

Details and patient eligibility

About

The aim of our study is to evaluate the effectiveness of proton pump inhibitor (PPI) treatment in patients with functional dyspepsia.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• aged 18-45 years with symptoms of dyspepsia,
• no evidence of organic disease.

Exclusion criteria

• Patients with alarm symptoms,
• Severe concomitant illness,
• Pregnancy or lactation,
• Alcohol or drug abuse,
• Use of aspirin or other non-steroidal anti-inflammatory drugs antibiotics, H2 receptor blockers, bismuth, or proton pump inhibitors in the preceding two weeks

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 2 patient groups, including a placebo group

pantoprazole

Experimental group

Treatment:

Drug: Pantoprazol

folic acid

Placebo Comparator group

Treatment:

Drug: Folic Acid