The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease

National Taiwan University

Status: Enrolling

Conditions: Pleural Diseases

Treatments: Procedure: different types of ultrasound technique

Study type: Interventional

Funder types: Other

Identifiers

NCT06226909

202311139RINC

Details and patient eligibility

About

To investigate the information from shear-wave elastography on pleural tissues will improve the diagnosis of pleural diseases, as to increase the diagnostic yield in ultrasound-guided transthoracic pleura biopsy.

Enrollment: 234 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with radiographic evidence of pleural disease

Exclusion criteria

• Age < 18 y/o
• Patients who cannot hold their breath for 5 seconds

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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234 participants in 2 patient groups

Shear-wave elastography-guided

Experimental group

Description:

based on the shear-wave elastography, the area with the highest elasticity value will be the target area to perform pleural biopsy for at least 6 times

Treatment:

Procedure: different types of ultrasound technique

B-mode ultrasound-guided

Active Comparator group

Description:

based on the B-mode transthoracic ultrasound, the area with the maximal thickness will be the target area to perform pleural biopsy for at least 6 times

Treatment:

Procedure: different types of ultrasound technique