The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia

Hamamatsu University

Status and phase: Completed; Phase 4

Conditions: Chronic Disease; Eosinophilic Pneumonia

Treatments: Drug: prednisolone 0.5 mg/kg/day for six months; Drug: prednisolone 0.5 mg/kg/day for three months

Study type: Interventional

Funder types: Other

Identifiers

NCT00632554

Hamamatsu-18-67

Details and patient eligibility

About

A comparison of 3 months-prednisolone administration with 6 months-prednisolone therapy in the treatment of chronic eosinophilic pneumonia. Three months-prednisolone administration may be as effective as 6 months-therapy.

Enrollment: 50 estimated patients

Sex: All

Ages: 16 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Biopsy-proven chronic eosinophilic pneumonia

Exclusion criteria

• Patients who received oral glucocorticosteroid (more than 10 mg)
• Immunosuppressive drug

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

1

Experimental group

Description:

prednisolone therapy for three months

Treatment:

Drug: prednisolone 0.5 mg/kg/day for three months

2

Active Comparator group

Description:

prednisolone therapy for six months

Treatment:

Drug: prednisolone 0.5 mg/kg/day for six months