The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)

Asan Medical Center

Status: Completed

Conditions: Chronic Interstitial Cystitis

Study type: Observational

Funder types: Other

Identifiers

NCT02331472

2014-1220

Details and patient eligibility

About

This study is to evaluate the efficacy of urine biomarker in patients with interstitial cystitis/painful bladder syndrome

Enrollment: 80 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. must have experienced bladder pain, urinary urgency and frequency for at least 6 months prior to entry into the study
2. Pain VAS >4
3. PUF score >13
4. ICQ score >12

4. cystoscopic record within 2years

Exclusion criteria

1. Patients who are pregnancy or, childbearing age without no contraception

2. Patient with microscopic hematuria, if not excluded that no evidence of neoplastic tumor examination

3. patients with urine culture showing evidence of urinary tract infection 1month prior to the study

4. Accompanied medical problem below

   • Tuberculosis in urinary system
   • Bladder cancer, urethral cancer, Prostate cancer
   • Recurrent cystitis
   • Anatomical disorder

5. Patients had prior surgery (bladder augmentation, cystectomy)

6. Patients with neurologic disorder

7. Patients with indwelling catheter or intermittent self-catheterization

8. Patients with psychological problem

Trial design

80 participants in 2 patient groups

Interstitial cystitis

Description:

Patients who have been diagnosed with interstitial cystitis/bladder pain syndrome. The group includes both patients with or without Hunner lesion on cystoscopy

Control

Description:

Adult participants without history of interstitial cystitis/bladder pain syndrome