The Efficacy of Using CR and PS Prosthesis in Total Knee Replacement

Air Force Military Medical University of People's Liberation Army

Status: Unknown

Conditions: Total Knee Arthroplasty

Treatments: Device: Cruciate-retaining (CR) prostheses; Device: Posterior-stabilized (PS) prostheses

Study type: Interventional

Funder types: Other

Identifiers

NCT03877042

XJ2018004

Details and patient eligibility

About

The investigators will investigate the efficacy of using CR and PS implants in TKA. The investigators will conduct TKA with different implants simultaneously on one patient to compare the post-operation efficacy of both implants.

Full description

A randomized, single-center, single group study comparing the efficacy and safety of using CR and PS implants in TKA. The investigators will conduct TKA with different implants simultaneously on one patient to compare the post-operation efficacy of both implants. Subjects will be monitored through postoperative follow-up to understand the bilateral knee condition.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients who plan to undergo primary total knee arthroplasty on bilateral knee joint with a diagnosis of osteoarthritis or rheumatoid arthritis, etc.;

Exclusion criteria

• Those who do not meet the inclusion criteria;
• Neuromuscular dysfunction;
• Diseases affecting postoperative efficacy evaluation

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Experimental

Experimental group

Description:

Patients with end-stage knee disease need Total Knee Arthroplasty in both knees.

Treatment:

Device: Cruciate-retaining (CR) prostheses

Device: Posterior-stabilized (PS) prostheses