The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment

IRCCS Centro Neurolesi "Bonino-Pulejo"

Status: Completed

Conditions: Alzheimer Disease; Multiple Sclerosis; Neurodegenerative Diseases; Cognitive Decline; Parkinson Disease Dementia

Treatments: Device: Vespa software

Study type: Interventional

Funder types: Other

Identifiers

NCT06281314

VESPA 2.0

Details and patient eligibility

About

VESPA 2.0 is based on an integrative and ecological approach used for the treatment of cognitive dysfunction in patients with MCI or other neurodegenerative disorders.

Full description

The goal of this study is to verify the effectiveness of the intensive-individual cognitive participation intervention (SCI-i) on the general cognitive functioning and specific cognitive functions of patients with mild or moderate cognitive decline affected by Alzheimer's dementia, Parkinson's and Multiple Sclerosis.

Participants will be subjected to cognitive training (tasks on attention, memory, language, executive functions, and visual-spatial functions) through software. They will take place using virtual cameras and virtual reality (VR) viewers. All subjects will undergo follow-up evaluation.

Enrollment: 60 patients

Sex: All

Ages: 50 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients diagnosed with Alzheimer Disease, Multiple Sclerosis, Parkinson Disease
• Severity of mild to moderate cognitive impairment
• Sign informed consent

Exclusion criteria

• Important comorbidities with psychiatric syndromes
• Failure to sign the informed consent
• Atypical parkinsonisms
• Clinical conditions that involve vision-related problems.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

Parkinson'disease group

Experimental group

Description:

Rehabilitation takes place with individual one-hour sessions per day. The stimulation intervention is organized on 4 different themes (chosen from orientation, memory, praxis, language, executive functions, attention, problem-solving, and functional activities) for 15' each.

Treatment:

Device: Vespa software

Multiple Sclerosis group

Experimental group

Description:

Rehabilitation takes place with individual one-hour sessions per day. The stimulation intervention is organized on 4 different themes (chosen from orientation, memory, praxis, language, executive functions, attention, problem-solving, and functional activities) for 15' each.

Treatment:

Device: Vespa software

Alzheimer group

Experimental group

Description:

Rehabilitation takes place with individual one-hour sessions per day. The stimulation intervention is organized on 4 different themes (chosen from orientation, memory, praxis, language, executive functions, attention, problem-solving, and functional activities) for 15' each.

Treatment:

Device: Vespa software