The Endoscopic Assesment of Intestinal Grafts (INTEGRATE)

Sahlgrenska University Hospital

Status: Unknown

Conditions: Enteritis; Transplant; Failure, Bowel; Transplant; Intestine; Mucosal Inflammation; Transplant; Complication, Rejection

Study type: Observational

Funder types: Other

Identifiers

NCT03444675

GBG18001

Details and patient eligibility

About

The study validates prospectively a new endoscopic scoring system (Gothenburg Intestinal Transplant Endoscopy Score, GITES) designed to summarize and stratify the abnormal ileal endoscopic findings after intestinal transplantation. GITES is a five-tier, four grade score which asseses mucosal friability, mucosal erythema and mucosal injury (ulcerations) as well as villous changes according to severity. These features (i.e., endoscopic descriptors) are also grouped from mild to very severe in the same sequence as observed during the progression of several pathologic conditions encountered after intestinal transplantation (acute rejection, infectious enteritis).

Enrollment: 80 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• transplantation of a segment of small intestine (as isolated graft or together with other organs)

Exclusion criteria

• contraindications for ileoscopy