The Epidemiology of Recurrent Spontaneous Abortion Associated With Thrombophilla

Shanghai First Maternity and Infant Hospital

Status: Unknown

Conditions: Recurrent Pregnancy Loss

Study type: Observational

Funder types: Other

Identifiers

NCT02990390

ShanghaiFMIH-0001

Details and patient eligibility

About

RSA is a multifactorial disorder resulting from genetic factors, anatomic factors, autoimmune disorders, endocrine dysfunction, thrombophilia, life style factors, and maternal infections. However, the underlying causes remain undetermined in up to 50% of cases. In this clinical cohort study, we intended to get an epidemiological evidence for patients with recurrent spontaneous abortion associated with thrombophilla.

Enrollment: 45,000 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Woman who had 2 miscarriages before 12(th) week of gestation.Signed consent form.

Exclusion criteria

1. having experienced severe allergies, trauma history and/or operation history within 3 months;
2. with a history of mental illness and/or family history of mental illness
3. limb disabled
4. taking medicine within one month
5. suffering major events or having mood swings
6. with a history of recurrent pregnancy loss
7. having internal and surgical disease(after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine routine)
8. chromosome aberrations in anyone of the couple.