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The Establishment of Advanced Brain Function Evaluation Model for Anterior Cruciate Ligament Reconstruction

Zhejiang University logo

Zhejiang University

Status

Unknown

Conditions

Anterior Cruciate Ligament Reconstruction;Resting State Functional Magnetic Resonance;Three-dimensional Gait Analysis;Return to Sports

Study type

Observational

Funder types

Other

Identifiers

NCT04715672
2020-144

Details and patient eligibility

About

It is difficult to establish the standard of return to sports post anterior cruciate ligament (ACL) reconstruction. The amplitude of low frequency fluctuation (ALFF) and functional connectivity (FC) of resting state functional magnetic resonance imaging (fMRI) can explore the differences in neural function of different populations, but have not been applied in the study of ACL postoperative return to sports.This project intends to use ALFF algorithm to calculate the changes of BLOD signals of coppers and non- coppers after ACL surgery in the subfrequency band and the functional network in the subfrequency band, explore the relationship between the default network (DMN) and the sensorimotor network (SMN), and use three-dimensional gait analysis to carry out accurate functional test..This project will explore the central strategy of ACL postoperative functional recovery from a new perspective, to provide a more reasonable high-level evaluation index for the timing of return to sports, and to reduce the incidence of postoperative re-tearing.

Enrollment

50 estimated patients

Sex

All

Ages

16 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients who completed the same operation and completed phased home rehabilitation instruction and who underwent ACL reconstruction more than 2 years after the operation were recruited as the test subjects

Exclusion criteria

heart and nervous system diseases, Other sports injuries such as medial collateral ligament injury, meniscus repair, grade III-IV cartilage injury, ankle instability, metal implants in the body and medication were excluded

Trial design

50 participants in 3 patient groups

copper
no-copper
normal

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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