The Evaluation Clinical Results of Coronally Advanced Flap With Platelet Rich Fibrin

Marmara University

Status: Completed

Conditions: Root Coverage

Treatments: Procedure: Connective tissue graft and coronally advanced flap; Procedure: Platelet rich fibrin and coronally advanced flap

Study type: Interventional

Funder types: Other

Identifiers

NCT04942821

22-04-2014/418

Details and patient eligibility

About

The aim of this study was to evaluate the clinical outcomes of platelet- rich fibrin and coronally advanced flap technique in the treatment of multiple gingival recessions in comparison with connective tissue graft technique.

Full description

Aim of this study was to evaluate the clinical outcomes of platelet rich fibrin (PRF)+coronally advanced flap (CAF) technique in the treatment of multiple gingival recessions in comparison with connective tissue graft (CTG)+CAF technique.12 patients with bilateral Miller Class I multiple gingival recessions were treated with PRF+CAF (test group) and CTG+CAF (control group) technique in a split-mouth study design. Probing depth, recession depth (RD), clinical attachment level (CAL), recession width, position of gingival margin, papilla width, keratinized tissue height (KTH), keratinized tissue thickness (KTT) were measured at baseline and 3, 6 and 12 months after surgery. Root coverage (RC) and complete root coverage (CRC) ratios were evaluated post-operatively.

Enrollment: 12 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients had at two quadrants, adjacent Miller Class I and at least 2 mm or deeper recessions
• Full mouth plaque score 20% and Full mouth bleeding on probing 10%
• no active periodontal disease,
• involving incisors, canines and premolars,
• age ≥ 18 years

Exclusion criteria

• Patients with general diseases which could affect healing process,
• smokers
• Patients had undergone periodontal surgery during the pervious 24 months on the involved sites,
• pregnant or breastfeeding women
• endodontic lesions or non-detectable cemento-enamel junctions at experimental teeth

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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12 participants in 2 patient groups

Platelet rich fibrin and coronally advanced flap

Experimental group

Description:

Coronally advanced flap and platelet rich fibrin were used in treatment arms.

Treatment:

Procedure: Platelet rich fibrin and coronally advanced flap

Connective tissue graft and coronally advanced flap

Active Comparator group

Description:

Coronally advanced flap and connective tissue graft were used in treatment arms.

Treatment:

Procedure: Connective tissue graft and coronally advanced flap