The Evaluation of Erector Spinae Plane Block for the Pain Control of Thoracic Postherpetic Neuralgia

Yonsei University

Status: Withdrawn

Conditions: Thoracic Postherpetic Neuralgia

Treatments: Procedure: erector spinae plane block (20 mL of 0.25% ropivacaine with dexamethasone 5mg); Procedure: thoracic paravertebral block(10 mL 0.25% ropivacaine with dexamethasone 5mg)

Study type: Interventional

Funder types: Other

Identifiers

NCT03595046

4-2018-0383

Details and patient eligibility

About

Erector spinae plane block is new interfascial plane block, and can be applied to management of thoracic neuropathic pain syndromes. The target of needle is deeper(or anterior) to the erector spinae muscle. So it is more safe and simple technique than prior technique, thoracic paravertebral block. The aim of this study is the evaluation of erector spinae plane block comparison to prevertebra block.

Full description

This study is single-blind because it is not possible to blind the practitioner performing the injection.

Subjects were randomly assigned to the erector spinae plane block group (group E) and the thoracic paravertebral block group (group P) by a random random number table, and the possibilities for belonging to any group were all the same and can not be artificially controlled by researchers.

Before the procedure, a resident who does not know of this study records the patient's pain and painDETECT. and on follow-up four weeks visits, PGIC scale is checked.

The erector spinae plane block or thoracic paravertebral block should be performed after receiving the informed consent of the patient.

Because of the large difference between the skilled and unskilled patients, the procedure in this study is performed by only one skilled practitioner.

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Inclusion criteria were patients who had chest wall post herpetic neuralgia, with moderate and severe pain and received appropriate antiviral therapy.

Exclusion criteria

1. Patient refusal
2. Patients who did not receive appropriate antiviral therapy
3. Patients with mild pain
4. Heavy skin eruption (no healthy area for needle entry) and infection at site of injection.
5. Patients with history of renal, hepatic diseases, coagulopathy, diabetes
6. Patients taking chemotherapy and/or radiotherapy
7. Patients with history of steroid therapy
8. Patients taking narcotic analgesics
9. Patient who does not understand the study because of illiteracy or language problems.
10. Abnormal findings in peripheral blood test (CBC, ESR, CRP, PT/aPTT)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups

erector spinae plane block group (group E)

Experimental group

Description:

ultrasound-guided erector spinae plane block

Treatment:

Procedure: erector spinae plane block (20 mL of 0.25% ropivacaine with dexamethasone 5mg)

thoracic paravertebral block group (group P)

Active Comparator group

Description:

ultrasound-guided thoracic paravertebral block

Treatment:

Procedure: thoracic paravertebral block(10 mL 0.25% ropivacaine with dexamethasone 5mg)