The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest

National Taiwan University

Status: Enrolling

Conditions: Cardiac Arrest

Treatments: Device: Head-up Cardiopulmonary Resuscitation

Study type: Interventional

Funder types: Other

Identifiers

NCT05609357

202204040DIND

Details and patient eligibility

About

Head up CPR with impedance threshold device(ITD) and active compression-decompression (ACD) has been proved to improve both cerebral and coronary perfusion pressure during resuscitation in animal models. Increased rates of Spontaneous Circulation (ROSC) were also observed in cardiac arrest patients.

The goal of this clinical trial is to learn about the feasibility and safety of Head-up Cardiopulmonary Resuscitation in patients with non-traumatic cardiac arrest. Participants will be received head-up CPR during resuscitation. The main question it aims to answer is if there is any adverse or unfavorable event during resuscitation.

Enrollment: 20 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Non-traumatic cardiac arrest
• Age ≥ 20

Exclusion criteria

• Trauma
• Age < 20
• Pregnancy
• Irreversible death (e.g. liver mortis, rigor mortis, decapitation, transection and decomposition)
• Disorder of cervical spine

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Head-up Cardiopulmonary Resuscitation

Experimental group

Treatment:

Device: Head-up Cardiopulmonary Resuscitation