The Feasibility of a Prehabilitation Program in the Liver Transplant Population at Barnes-Jewish Hospital

The Washington University

Status: Completed

Conditions: Physical Activity; End Stage Liver Disease

Treatments: Procedure: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT02444273

201403118

Details and patient eligibility

About

The primary outcome of this study is to demonstrate the feasibility of a prehabilitation program at Barnes Jewish Hospital for liver transplant candidates. Those patients who consent to participate in the study and are placed on the transplant list will be randomized into either the control or intervention group. The intervention group receives a personalized home exercise program along with weekly phone calls to provide coaching, mentoring and motivation. Data collected at baseline, post-transplant and, post-transplant follow up will be compared among the two study groups. The secondary outcomes include: normative data of functional measures for patients with end stage liver disease and to determine the effect size for future research on prehabilitation in the patient population.

Enrollment: 101 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being evaluated for liver transplantation by Barnes Jewish Hospital medical team

Exclusion criteria

• Non-english speaking
• Medical contraindications to exercise as determined by the medical team

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

101 participants in 2 patient groups

Control Group

No Intervention group

Description:

Subjects will receive standard care both pre and post transplant.

Exercise Group

Experimental group

Description:

Subjects will receive a personalized home exercise program and regular phone calls from a therapist to monitor and promote activity.

Treatment:

Procedure: Exercise