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The Genetic Basis for Vulnerability to Substance Abuse

National Institutes of Health (NIH) logo

National Institutes of Health (NIH)

Status

Completed

Conditions

Substance Abuse

Treatments

Procedure: Blood draw

Study type

Observational

Funder types

NIH

Identifiers

NCT00247819
NIDA-IRP-148

Details and patient eligibility

About

This investigation seeks to better define the genetic basis for vulnerability to substance abuse.

Full description

Dopamine (DA), a neurotransmitter helping to mediate reward and reinforcement, has been putatively linked to the development of substance abuse, alcohol abuse, and alcoholism. Identification of specific vulnerability-association alleles for receptors, other molecules within the reward mediating system, and other genes that may predispose individuals to the development of such disorders is the goal of the study.

This investigation will help elucidate the genetic underpinnings of substance abuse, potentially leading to the improved methods to diagnose those at risk and to help develop better therapeutic interventions.

Enrollment

8,000 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Substance abusers
  • Allow for blood draw

Exclusion criteria

  • Cognitively impaired

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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