The Genetics of Pulmonary Fibrosis

University of Colorado Denver (CU Denver)

Status: Enrolling

Conditions: Idiopathic Pulmonary Fibrosis (IPF)

Treatments: Other: Blood draw; Other: Questionnaire

Study type: Observational

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT03478553

15-1147

W81XWH-17-1-0597_1a (Other Grant/Funding Number)

Details and patient eligibility

About

This study seeks to screen first degree family members of people with Idiopathic Pulmonary Fibrosis (IPF) for the earliest signs of lung fibrosis.

Full description

The purpose of this study is to explore genetic factors associated with the development of pulmonary fibrosis. The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis. To investigate the genetics of pulmonary fibrosis, the investigators plan to enroll individuals with pulmonary fibrosis and their family members.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age at least 18 years old
• Family member diagnosed with IPF

Exclusion criteria

• No family member with IPF

Trial design

1,000 participants in 2 patient groups

People with IPF

Treatment:

Other: Questionnaire

Other: Blood draw

Family members without IPF

Treatment:

Other: Questionnaire

Other: Blood draw