The Glycemic and Insulinemic Responses Elicited by Meals Containing Whole Grain Rye Bread or White Wheat Bread

University of Helsinki

Status: Unknown

Conditions: Blood Glucose Concentration

Treatments: Other: soup; Other: margarine; Other: rye bread; Other: ham; Other: Wheat bread

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02400411

HY_RAV_Breadmeal

Details and patient eligibility

About

This is a postprandial study with healthy volunteers. The glycemic and insulinemic responses elicited by meals containing either whole grain rye bread or white wheat bread as such or combined with margarine and ham and vegetable soup are compared. Blood glucose concentrations are monitored from finger prick blood samples collected before the meal and at 15, 30, 45, 60, 90 and 120 min. Venous samples for insulin concentrations are taken at time-points 0, 30 and 60 min.

Enrollment: 15 estimated patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female
• BMI 18-27 kg/m2

Exclusion criteria

• pregnant or breastfeeding
• diabetes, gastrointestinal disease
• regular use of medication
• strict vegetarian or vegan diet
• food allergy
• recent blood donation

Trial design

15 participants in 6 patient groups

Wheat bread

Experimental group

Description:

Bread-based meal

Treatment:

Other: Wheat bread

Wheat bread with margarine and ham

Experimental group

Description:

Bread-based meal

Treatment:

Other: margarine

Other: ham

Other: Wheat bread

Wheat bread with margarine, ham and soup

Experimental group

Description:

Bread-based meal

Treatment:

Other: margarine

Other: soup

Other: ham

Other: Wheat bread

Rye bread

Experimental group

Description:

Bread-based meal

Treatment:

Other: rye bread

Rye bread with margarine and ham

Experimental group

Description:

Bread-based meal

Treatment:

Other: margarine

Other: ham

Other: rye bread

Rye bread with margarine, ham and soup

Experimental group

Description:

Bread-based meal

Treatment:

Other: margarine

Other: soup

Other: ham

Other: rye bread