The Guidance of Thin Cross- Section of CT in Anatomic Segmentectomy

The Second Hospital of Shandong University

Status: Completed

Conditions: Thin Cross- Section of CT; Three-dimensional-computed Tomography (3D-CT); Video- Assisted Thoracoscopic Surgery; Segmentectomy

Treatments: Other: Cross- Section of CT Guided Anatomic Segmentectomy; Other: 3D simulation Guided Anatomic Segmentectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04842578

thin cross- section of CT ZYP

Details and patient eligibility

About

Three-dimensional (3D) simulation of pulmonary vessels and the space between the lesion and adjacent tissues is regarded improving the safety and accuracy of video-assisted thoracoscopic surgery (VATS) for segmentectomy for ground glass opacity (GGO) in lung. However, not every thoracic surgeon can handle the technique, in addition, the 3D reconstruction originate from the thin CT scan. Actually, the investigators found that, the reading and comprehension of the thin cross- section of CT can guide the accurate anatomic segmentectomy in most situations. The investigators designed a retrospective study to compare the reading of thin cross- section of CT with 3D reconstruction or without 3D reconstruction during the guidance of anatomic segmentectomy.

Enrollment: 200 patients

Sex: All

Ages: 25 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Selection criteria for VATS segmentectomy in the present study were as follows:

(I) patients with single peripheral GGO lesion considered suspicious for malignancy;

(II) the lesion <2 cm in diameter and with at least one of the followings:

(i) pure adenocarcinoma in situ (AIS) histology;

(ii) nodule has ≥50% ground-glass appearance on high resolution CT;

(iii) radiologic surveillance conforms a long doubling time (≥400 days).

Exclusion criteria

(I) patients with insufficient cardiopulmonary function;

(II) other contraindication for segmentectomy.

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

group of thin cross- section of CT

Experimental group

Description:

Anatomic Segmentectomy with the Guidance of Thin Cross- Section of CT

Treatment:

Other: Cross- Section of CT Guided Anatomic Segmentectomy

group of thin 3D simulation

Active Comparator group

Description:

Anatomic Segmentectomy with the Guidance of 3D simulation

Treatment:

Other: 3D simulation Guided Anatomic Segmentectomy